Welcome to RNAmigos.
RNAmigos takes as input either a PDB file of an RNA structure, or a graph with base pairing information.
The input structure is used to predict a small molecule binding profile (molecular fingerprint).
If you specify a small molecule library, we scan it using the predicted fingerprint and return the most similar compounds.
Click HERE for detailed instructions.
Contact : Carlos Oliver (rnamigos[at]cs.mcgill[doca])
Source
@article{oliver2020augmented, title={Augmented base pairing networks encode RNA-small molecule binding preferences}, author={Oliver, Carlos and Mallet, Vincent and Gendron, Roman Sarrazin and Reinharz, Vladimir and Hamilton, William L and Moitessier, Nicolas and Waldisp{\"u}hl, J{\'e}r{\^o}me}, journal={Nucleic acids research}, volume={48}, number={14}, pages={7690--7699}, year={2020}, publisher={Oxford University Press} }