Welcome to RNAmigos.

RNAmigos takes as input either a PDB file of an RNA structure, or a graph with base pairing information.

The input structure is used to predict a small molecule binding profile (molecular fingerprint).

If you specify a small molecule library, we scan it using the predicted fingerprint and return the most similar compounds.

Click HERE for detailed instructions.

Contact : Carlos Oliver (rnamigos[at]cs.mcgill[doca])
Source

You can leave either of these fields empty to get a sample.

Step 1 Upload RNA PDB or Graph (see help for format, default is 2 TAR-ARGININAMIDE Binding Site)


Step 2 Upload Ligand Library (optional)


Citing

@article{oliver2020augmented,
  title={Augmented base pairing networks encode RNA-small molecule binding preferences},
  author={Oliver, Carlos and Mallet, 
  Vincent and Gendron, Roman Sarrazin and Reinharz, 
  Vladimir and Hamilton, William L and Moitessier, 
  Nicolas and Waldisp{\"u}hl, J{\'e}r{\^o}me},
  journal={Nucleic acids research},
  volume={48},
  number={14},
  pages={7690--7699},
  year={2020},
  publisher={Oxford University Press}
}